First IORT Treatment in Northern Virginia
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First IORT Treatment in Northern Virginia 

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Intraoperative Radiation Therapy (IORT) with the Xoft System Provides Single, Targeted Dose of Radiation Therapy During Lumpectomy

Woodbridge,  VA– May 16, 2013 – Sentara Northern Virginia Medical Center today announced that the Xoft® Axxent® Electronic Brachytherapy System® is now available to treat patients with early stage breast cancer and that the first patient was treated there on May 16, 2013.

The Xoft system, when utilized for Intraoperative Radiation Therapy (IORT), delivers a single, prescribed, targeted dose of isotope-free radiation directly to the tumor cavity during surgery, thereby minimizing radiation to healthy tissue and organs and eliminating the need for a shielded treatment environment. Typical radiation therapy methods for breast cancer include whole breast radiation, which involves daily treatments for five to seven weeks, and partial breast irradiation where 10 treatments are delivered over a period of five days.

“At Sentara Northern Virginia Medical Center we are committed to providing the most advanced treatment options, like the Xoft system, in order to provide the best possible care to our patients,” said Megan Perry, President of Sentara Northern Virginia Medical Center. “The Xoft system will first be offered to patients with early stage breast cancer who are eligible for IORT and will later be used for the treatment of endometrial and skin cancers.” 

“Our team is very excited to add electronic brachytherapy to our slate of life-saving treatment methods.  The ability to utilize isotope-free, electronic treatment that effectively targets the cancer site while minimizing radiation exposure to healthy tissues is something we are proud to make available to our patients." said Dr. Negar Golesorkhi, MD.  

Sentara Northern Virginia Medical Center will also participate in a post-market clinical study of the Xoft system for IORT. The study, “A Safety and Efficacy Study of Intra-Operative Radiation Therapy (IORT) Using the Xoft Axxent eBx System at the Time of Breast Conservation Surgery for Early-Stage Breast Cancer,” is a prospective, multi-center, historical control trial. Researchers plan to enroll up to 1,000 patients at as many as 50 study sites across the U.S. and Europe. This post-market study aims to demonstrate the long-term efficacy of IORT with Xoft compared to external beam irradiation and assess cosmetic outcomes and quality of life.  “We are pleased to be able to offer this innovative technology to patients who meet the clinical criteria for this breast cancer treatment; we are certain that it will make patient treatment and recovery less distressing during what can be an anxious time,” according to Dr. Susan Boylan, MD.

The Sentara Northern Virginia Auxiliary has made a $250,000 pledge to support the Xoft system at Sentara Northern Virginia Medical Center.

“We are very excited to support such an important project,” says Joyce Pieritz, President of the Auxiliary. “Our members are dedicated to supporting new technologies and services because we know that our entire community will benefit.”

About Sentara Northern Virginia Medical Center

Sentara Northern Virginia Medical Center is a 183-bed, not-for-profit community hospital in Prince William County, Virginia. We uphold the Sentara Healthcare mission to Improve Health Every Day by offering a wide range of medical specialties, a highly qualified medical and clinical staff, and state-of-the-art technology, including Sentara eCare Health Network, a fully integrated electronic medical record.

About Sentara Northern Virginia Medical Center Breast Health Centers

Sentara breast health services in Northern Virginia are provided by Sentara Northern Virginia Comprehensive Breast Center (SNVCBC), which offers multidisciplinary approach to breast health care in several locations.

SNVCBC has achieved recognition for excellence from two national organizations that recognize quality and excellence in breast health providers. For patients, a breast center that achieves accreditation means that the facility has demonstrated a firm commitment to offer its patients every advantage in their breast health and battle against breast disease. SNVMC is accredited by National Accreditation Program for Breast Center (NAPBC), a program administered by the American College of Surgeons.  Receiving care at a NAPBC-accredited center ensures that a patient will have access to comprehensive care, including a full range of state-of-the-art services, a multidisciplinary team approach to coordinate the best treatment options, and information about ongoing clinical trials and new treatment options, and most importantly, quality breast care close to home.

SNVCBC is also designated as an American College of Radiology Breast Imaging Center of Excellence. By awarding facilities the status of a Breast Imaging Center of Excellence, the ACR recognizes breast imaging centers that have earned accreditation in mammography, stereotactic breast biopsy, and breast ultrasound, including ultrasound-guided breast biopsy.

All SNVCBC locations utilize state of the art digital mammography technology, including computer-aided detection (CAD), and offer convenient choices for breast health care close to home. Each is supported by the Sentara eCare Health Network®, a secured electronic medical record system.

About Xoft

The Xoft eBx® Electronic Brachytherapy System from iCAD is an isotope-free radiation treatment cleared by the FDA for use anywhere in the body, including for the treatment of early stage breast cancer, endometrial cancer and skin cancer. It utilizes a proprietary miniaturized x-ray as the radiation source that delivers precise treatment directly to cancerous areas while sparing healthy tissue and organs. The Xoft system can be administered as a single course of radiation therapy during surgery in the form of intraoperative radiation therapy (IORT) or in the form of partial breast irradiation (APBI). The Xoft system does not require a shielded environment and the system’s relatively small size and mobility enable it to be used in virtually any clinical setting. For more information about Xoft visit


Sentara Healthcare

Rebecca Tiffany


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