Clinical Trials

Sentara Vascular Specialists physicians are committed to improving lives of patients who have vascular disease which are diseases of the blood vessels - the arteries and veins of the circulatory system of the body. Vascular disease is a subgroup of cardiovascular disease. Sentara Vascular Specialists has access to cutting edge clinical trials that focus on the treatment of vascular disease.

For more information on these clinical trials and studies, please contact Sentara Vascular Specialists at 757-395-1600757-395-1600 and ask to speak with a Research coordinator.

  • Thoracic Aneurysms and Dissections

    Current clinical research studies involving aneurysms (ballooning or dilatation of a vessel) and dissections ( tear in the vessel wall) in the arch of the ascending and/or descending thoracic aorta. The clinical trials are evaluating the safety and effectiveness of investigational endovascular devices that will treat these modalities

  • Abdominal Aortic Aneurysms

    A current clinical research study to evaluate the safety and effectiveness of an investigational endovascular device for the treatment of abdominal aortic aneurysms.

  • Carotid Disease

    A current clinical research study of carotid stenosis (blockage in the carotid artery) in individuals that have asymptomatic carotid disease that is greater than 70% or individuals that are symptomatic with greater than 50% carotid stenosis. The clinical trial is researching the safety and effectiveness of a cerebral protection device to obtain and establish the safety and efficacy of a device for providing cerebral embolic protection during angioplasty and stenting procedures in carotid arteries. The device also facilitates access to the carotid and neuro anatomy for the introduction of therapeutic or diagnostic endovascular devices and/or agents.

  • Peripheral Vascular Disease

    Current clinical research trials to evaluate the safety and efficacy of investigational devices for treating blockages in the arteries of the lower extremities.

  • Venous Disease

    A clinical trial to collect confirmatory evidence of the safety and effectiveness of a venous iliac vein stent for the treatment of iliofemoral venous occlusive disease, including acute or chronic deep vein thrombosis (DVT), May-Thurner Syndrome, and/or any combination of the modalities named.

  • Renal Failure/Dialysis Access

    The vascular practice currently creates hemodialysis access in the form of autologous arteriovenous dialysis fistula (AVF) or prosthetic graft (AVG).  There is a high rate of dysfunction of the dialysis access mainly because of the development of neo-intimal hyperplasia response that results in the formation of stenotic (blockages) lesions at the site where the artery and vein are sewn together to create the fistula (AVF) and/or along the venous outflow tract (vein taking the blood back to the heart).  The site is currently involved in a randomized clinical research trial involving standard percutaneous transluminal angioplasty balloon catheter treatment versus a drug coated percutaneous transluminal angioplasty balloon catheter for the treatment of obstructive (blockage) lesions in the fistula.